Sorbentless Dried Blood Spot Sampling for Automated DBS Analysis

0586986 - ÚIACH 2025 CZ eng A - Abstrakt
Dvořák, Miloš - Profousová, Sylvie - Kubáň, Pavel
Sorbentless Dried Blood Spot Sampling for Automated DBS Analysis.
MSB 2024. Final Program and Abstract Book. Brno: Ústav analytické chemie AV ČR, v. v. i., 2024 - (Lavická, J.; Přikryl, J.; Foret, F.). s. 138-138. ISBN 978-80-908154-1-4.
[MSB 2024. International Symposium on Microscale Separation and Bioanalysis /40./. 19.05.2024-22.05.2024, Brno]
Grant CEP: GA ČR(CZ) GA23-05972S
Institucionální podpora: RVO:68081715
Klíčová slova: dried blood spot (DBS) * blood
Obor OECD: Analytical chemistry
https://www.msb2024.org/user_uploads/program/Program_and_Abstract_Book_final.pdf

At present, the majority of dried blood spot (DBS) samples are collected on cellulose-based sampling cards. Recently, novel sampling materials and approaches were developed as attractive alternatives for blood
collection. The rationale for their development was the detrimental effect of blood hematocrit on quantitative DBS analysis, the reduced elution recoveries of analytes, and the limited suitability for patient-centric blood collection of standard DBS cards. Moreover, porous sampling sorbents contain random production-borne species that can be released during sample preparation and contaminate the resulting eluate.
Trvalý link: https://hdl.handle.net/11104/0354313