The strength of gut microbiota transfer along social networks and genealogical lineages in the house mouse

0586656 - ÚBO 2025 RIV US eng J - Článek v odborném periodiku
Bendová, Barbora - Vošlajerová Bímová, Barbora - Čížková, Dagmar - Daniszová, Kristina - Ďureje, Ľudovít - Hiadlovská, Zuzana - Macholán, Miloš - Piálek, Jaroslav - Schmiedová, Lucie - Kreisinger, J.
The strength of gut microbiota transfer along social networks and genealogical lineages in the house mouse.
FEMS Microbiology Ecology. Roč. 100, č. 6 (2024), č. článku fiae075. ISSN 0168-6496. E-ISSN 1574-6941
Grant CEP: GA ČR(CZ) GA19-19307S; GA ČR GAP506/11/1792
Institucionální podpora: RVO:68081766 ; RVO:67985904
Klíčová slova: gastrointestinal tract * inter-individual transmission * microbiome * relatedness * social contact
Obor OECD: Microbiology
Impakt faktor: 4.2, rok: 2022
Způsob publikování: Open access
https://academic.oup.com/femsec/article/100/6/fiae075/7668476?login=true

The gut microbiota of vertebrates is acquired from the environment and other individuals, including parents and unrelated conspecifics. In the laboratory mouse, a key animal model, inter-individual interactions are severely limited and its gut microbiota is abnormal. Surprisingly, our understanding of how inter-individual transmission impacts house mouse gut microbiota is solely derived from laboratory experiments. We investigated the effects of inter-individual transmission on gut microbiota in two subspecies of house mice (Mus musculus musculus and M. m. domesticus) raised in a semi-natural environment without social or mating restrictions. We assessed the correlation between microbiota composition (16S rRNA profiles), social contact intensity (microtransponder-based social networks), and mouse relatedness (microsatellite-based pedigrees). Inter-individual transmission had a greater impact on the lower gut (colon and cecum) than on the small intestine (ileum). In the lower gut, relatedness and social contact independently influenced microbiota similarity. Despite female-biased parental care, both parents exerted a similar influence on their offspring's microbiota, diminishing with the offspring's age in adulthood. Inter-individual transmission was more pronounced in M. m. domesticus, a subspecies, with a social and reproductive network divided into more closed modules. This suggests that the transmission magnitude depends on the social and genetic structure of the studied population.
Trvalý link: https://hdl.handle.net/11104/0354089