Metabolic effects of n-3 fatty acids administered as Calanus oil in dietary obese mice with modified PPARα expression

0583501 - FGÚ 2024 RIV US eng A - Abstrakt
Horáková, Olga - Kalendová, Veronika - Čajka, Tomáš - Rossmeisl, Martin
Metabolic effects of n-3 fatty acids administered as Calanus oil in dietary obese mice with modified PPARα expression.
European Journal of Clinical Investigation. Wiley. Roč. 53, Suppl.1 (2023), č. článku 57ASM-231. ISSN 0014-2972. E-ISSN 1365-2362.
[ANNUAL SCIENTIFIC MEETING /57./. 07.06.2023-09.06.2023, Praha]
Grant CEP: GA MŠMT(CZ) LX22NPO5104
Institucionální podpora: RVO:67985823
Klíčová slova: polyunsaturated fatty acids * EPA * DHA
Obor OECD: Endocrinology and metabolism (including diabetes, hormones)
https://onlinelibrary.wiley.com/doi/10.1111/eci.13992

Chronic Calanus oil administration may alter hepatic lipid profile independently of functional PPARalpha presence. However, its beneficial effects may only occur upon conditions of significantly increased he-patic steatosis, probably due to some indirect mechanisms induced outside the liver.
Trvalý link: https://hdl.handle.net/11104/0351471