Počet záznamů: 1
Role of insulin and Uncoupling protein 1 in glucose lowering effect of β3-adrenergic stimulation
- 1.0583487 - FGÚ 2024 RIV US eng A - Abstrakt
Zouhar, Petr
Role of insulin and Uncoupling protein 1 in glucose lowering effect of β3-adrenergic stimulation.
European Journal of Clinical Investigation. Wiley. Roč. 53, Suppl.1 (2023), č. článku 57ASM-118. ISSN 0014-2972. E-ISSN 1365-2362.
[ANNUAL SCIENTIFIC MEETING /57./. 07.06.2023-09.06.2023, Praha]
Grant CEP: GA MŠMT(CZ) LX22NPO5104
Institucionální podpora: RVO:67985823
Klíčová slova: insulin * brown adipose tissue * glucose * UCP1
Obor OECD: Endocrinology and metabolism (including diabetes, hormones)
https://onlinelibrary.wiley.com/doi/10.1111/eci.13992
Despite the ability of CL 316243 to stimu-late glucose uptake into brown adipocytes, the systemic glucose- lowering effect of CL 316243 is dependent on the presence of insulin but not of UCP1. Even in the absence of its glucose- burning properties, brown adipose tissue may be an important mediator of the glucose- lowering ef-fects of β3- adrenergic stimulation.
Trvalý link: https://hdl.handle.net/11104/0351454
Počet záznamů: 1