Synergetic radical-scavenging effect in the complex of copper(II) with the thiosemicarbazone of salicylaldehyde

0579599 - FZÚ 2024 RIV GB eng J - Článek v odborném periodiku
Andriichuk, Y.M. - Lyapunov, A.Y. - Hotynchan, A.H. - Savchenko, Dariia - Karavan, V.V. - Turash, M.M. - Khalavka, Y.B.
Synergetic radical-scavenging effect in the complex of copper(II) with the thiosemicarbazone of salicylaldehyde.
Journal of Coordination Chemistry. Roč. 76, 13-15 (2023), s. 1763-1775. ISSN 0095-8972. E-ISSN 1029-0389
Grant CEP: GA MŠMT(CZ) EF16_019/0000760
Grant ostatní: OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institucionální podpora: RVO:68378271
Klíčová slova: salicylaldehyde thiosemicarbazone * metal complex * antioxidant * DPPH Assay
Obor OECD: Inorganic and nuclear chemistry
Impakt faktor: 1.9, rok: 2022
Způsob publikování: Omezený přístup
https://doi.org/10.1080/00958972.2023.2261603

The radical scavenging activities of salicylaldehyde thiosemicarbazone and its copper(II) and cadmium(II) complexes were evaluated by in vitro experiments in the reaction with 2,2'-diphenyl-1-picrylhydrazyl. Salicylic aldehyde thiosemicarbazone complex with Cu(II) shows significantly higher radical-scavenging activity than Cu2+ ions, salicylaldehyde thiosemicarbazone, and Cd(II) complex. Electrochemical, EPR and kinetic studies revealed that the high rate of reaction and efficiency is due to the mechanism of electron transfer, which is enhanced by the synergetic effect of the ligand structure and the ability of the copper ion to exhibit variable valencies.

Trvalý link: https://hdl.handle.net/11104/0349091