A new promising material for biological applications: multilevel physical modification of AgNP-decorated PEEK

0578835 - ÚMCH 2024 RIV CH eng J - Článek v odborném periodiku
Pryjmaková, J. - Grossberger, D. - Kutová, A. - Vokatá, B. - Šlouf, Miroslav - Slepička, P. - Siegel, J.
A new promising material for biological applications: multilevel physical modification of AgNP-decorated PEEK.
Nanomaterials. Roč. 13, č. 24 (2023), č. článku 3079. E-ISSN 2079-4991
Institucionální podpora: RVO:61389013
Klíčová slova: polyetheretherketone * immobilisation * physical modification
Obor OECD: Polymer science
Impakt faktor: 5.3, rok: 2022
Způsob publikování: Open access
https://www.mdpi.com/2079-4991/13/24/3079

In the case of polymer medical devices, the surface design plays a crucial role in the contact with human tissue. The use of AgNPs as antibacterial agents is well known, however, there is still more to be investigated about their anchoring into the polymer surface. This study describes the changes in the surface morphology and behaviour in the biological environment of polyetheretherketone (PEEK) with immobilised AgNPs after different surface modifications. The initial composites were prepared by immobilising silver nanoparticles from a colloid solution in the upper surface layers of polyetheretherketone (PEEK). The prepared samples (Ag/PEEK) had a planar morphology and were further modified with a KrF laser, a GaN laser, and an Ar plasma. The samples were studied using the AFM method to visualise changes in surface morphology and obtain information on the height of the structures and other surface parameters. A comparative analysis of the nanoparticles and polymers was performed using FEG-SEM. The chemical composition of the surface of the samples and optical activity were studied using XPS and UV-Vis spectroscopy. Finally, drop plate antibacterial and cytotoxicity tests were performed to determine the role of Ag nanoparticles after modification and suitability of the surface, which are important for the use of the resulting composite in biomedical applications.
Trvalý link: https://hdl.handle.net/11104/0349273