Diastereomeric Resolution of 9,10-diketo[7]Helicene and its Use in One-step Preparation of Helicene-based D-A-D Push-pull Systems

0577922 - ÚCHP 2024 CZ eng A - Abstrakt
Kos, Martin - Beránek, Tomáš - Císařová, I. - Cuřínová, Petra - Žádný, Jaroslav - Storch, Jan - Církva, Vladimír - Jakubec, Martin
Diastereomeric Resolution of 9,10-diketo[7]Helicene and its Use in One-step Preparation of Helicene-based D-A-D Push-pull Systems.
Book of Abstracts. Prague: Czech Chemical Society, 2023. s. 81, č. článku Poster 11..
[Advances in Organic, Bioorganic and Pharmaceutical Chemistry /57./. 09.11.2023-11.11.2023, Špindlerův Mlýn]
Grant CEP: GA MV(CZ) VJ01010065
Institucionální podpora: RVO:67985858
Klíčová slova: helicenes * enantiopure * push-pull systems
Obor OECD: Organic chemistry

This work presents a novel method for achieving the optical resolution of 9,10-diketo-[7]helicene1, a highly versatile building block with broad applications in helicene based molecule synthesis. Our study has revealed that diketone 1 exhibits exceptional reactivity with both (S)- and (R)-1,1′-binaphthyl-2,2′-diamine, resulting in superior diastereomeric excess.
Trvalý link: https://hdl.handle.net/11104/0347002