Microfluidic trends in drug screening and drug delivery

0574540 - BTÚ 2024 RIV GB eng J - Článek v odborném periodiku
Feng, J. - Neužil, Jiří - Manz, A. - Iliescu, C. - Neužil, P.
Microfluidic trends in drug screening and drug delivery.
TrAC-Trends in Analytical Chemistry. Roč. 158, JAN 2023 (2023), č. článku 116821. ISSN 0165-9936. E-ISSN 1879-3142
Institucionální podpora: RVO:86652036
Klíčová slova: Microfluidic technologies * Drug screening * Drug delivery * Drug discovery
Obor OECD: Analytical chemistry
Impakt faktor: 13.1, rok: 2022
Způsob publikování: Open access
https://www.sciencedirect.com/science/article/pii/S0165993622003041?via%3Dihub

The low probability of a drug candidate's clinical success, the time consumed and the high cost of bringing a drug from concept to market emphasizes the need for new approaches to drug discovery. Recent innovations in microfluidic technologies, including organ-on-a-chip, droplet microfluidics and high-throughput screening are revealing the potential of these platforms to address some of these challenges, due to the small volume of samples consumed, short processing time, and improved process control. Here, we review selected recent progress in the development and application of microfluidic technologies in drug screening and drug delivery, highlighting the trends and associated challenges.& COPY, 2022 Published by Elsevier B.V.
Trvalý link: https://hdl.handle.net/11104/0345464