A novel water‑soluble thiosemicarbazone Schiff base ligand and its complexes as potential anticancer agents and cellular fluorescence imaging

0574229 - FZÚ 2024 RIV DE eng J - Článek v odborném periodiku
Feizpour, S. - Hosseini‑Yazdi, S.A. - Safarzadeh, E. - Baradaran, B. - Dušek, Michal - Poupon, Morgane
A novel water‑soluble thiosemicarbazone Schiff base ligand and its complexes as potential anticancer agents and cellular fluorescence imaging.
Journal of Biological Inorganic Chemistry. Roč. 28, č. 5 (2023), s. 457-472. ISSN 0949-8257. E-ISSN 1432-1327
Grant CEP: GA MŠMT(CZ) EF16_019/0000760
Grant ostatní: OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institucionální podpora: RVO:68378271
Klíčová slova: anticancer activity * apoptosis * cell cycle * cytotoxicity * flow cytometry * x-ray crystallography
Obor OECD: Condensed matter physics (including formerly solid state physics, supercond.)
Impakt faktor: 3, rok: 2022
Způsob publikování: Omezený přístup
https://doi.org/10.1007/s00775-023-02001-5

A novel fluorescent ligand (H2LCl⋅1.5CH3OH, 1) was synthesized and metal complexes of 1 with Mn(II), Fe(III), Ni(II), Cu(II), and Zn(II) were obtained as Mn(HL)2Cl2 (2), Fe(HL)2Cl3⋅3H2O (3), Ni(L)(HL)Cl⋅8H2O (4), Cu(HL)Cl2⋅4H2O (5), Zn(H2L)Cl3 (6), respectively. These compounds were identified by spectroscopic methods, elemental analysis, molar conductivity, and single-crystal X-ray crystallography.
Trvalý link: https://hdl.handle.net/11104/0344571