Homobimetallic Au(I)–Au(I) and heterotrimetallic Au(I)–Fe(II)–Au(I) complexes with dialkyldithiophosphates and phosphine ligands: structural characterization, DFT analysis, and tyrosinase inhibitory and biological effects

0573645 - FZÚ 2024 RIV US eng J - Článek v odborném periodiku
Neshat, A. - Mahdavi, A. - Yousefshahi, R.Y. - Cheraghi, M. - Mobarakeh, A.M. - Mohammadi, S. - Eigner, Václav - Kučeráková, Monika - Dušek, Michal - Kaboudin, B.
Homobimetallic Au(I)–Au(I) and heterotrimetallic Au(I)–Fe(II)–Au(I) complexes with dialkyldithiophosphates and phosphine ligands: structural characterization, DFT analysis, and tyrosinase inhibitory and biological effects.
ACS Omega. Roč. 8, č. 23 (2023), s. 20423-20439. ISSN 2470-1343. E-ISSN 2470-1343
Grant CEP: GA MŠMT(CZ) EF16_019/0000760
Grant ostatní: OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institucionální podpora: RVO:68378271
Klíčová slova: gold * ligands * mathematical methods * metals * crystal structure * X-ray diffraction
Obor OECD: Condensed matter physics (including formerly solid state physics, supercond.)
Impakt faktor: 4.1, rok: 2022
Způsob publikování: Open access

The role of bridging and terminal ligand electronic and steric properties on the structure and antiproliferative activity of two-coordinated gold(I) complexes was investigated on seven novel binuclear and trinuclear gold(I) complexes. In 1−7, the gold(I) centers adopt a two-coordinated linear geometry and are structurally similar. However, their structural features and antiproliferative properties highly depend upon subtle ligand substituent changes. All complexes were validated by 1H, 13C{1H}, 31P NMR, and IR spectroscopy. The solid-state structures of 1, 2, 3, 6, and 7 were confirmed using single-crystal X-ray diffraction.
Trvalý link: https://hdl.handle.net/11104/0344040