Počet záznamů: 1
Synthesis and cytotoxicity of fluorinated mannosamines
- 1.0572648 - ÚCHP 2024 CZ eng K - Konferenční příspěvek (tuzemská konf.)
Krčil, Aleš
Synthesis and cytotoxicity of fluorinated mannosamines.
Proceedings of Abstracts. Prague: Institute of Chemical Process Fundamentals of the CAS, v. v. i., 2023 - (Bendová, M.; Wagner, Z.; Windell, L.), s. 18-19. ISBN 978-80-86186-29-0.
[Bažant postraguate conference 2023. Prague (CZ), 31.05.2023-01.06.2023]
Institucionální podpora: RVO:67985858
Klíčová slova: synthesis * cytotoxicity * fluorinated mannosamines
Obor OECD: Organic chemistry
The aim of the project is to synthesise mono-, di- and trifluoroanalogs of N-acetylmannosamines. The cytotoxicity of the final products towards selected cancer cells will be determined. The key intermediates are the corresponding multiply fluorinated mannosazidethioglycosides prepared from deoxyfluorinated 1,6-anhydro-2-azidoβ-D-hexopyranose precursors by ring-opening reactions with phenyltrimethylsilyl sulfide.
Trvalý link: https://hdl.handle.net/11104/0343248
Počet záznamů: 1