Feature-overlapper: The tool for DNA analysis overlap

0571535 - BFÚ 2024 RIV NL eng J - Článek v odborném periodiku
Havlík, J. - Brázda, Václav - Stanek, K. - Ježek, M. - Šťastný, J.
Feature-overlapper: The tool for DNA analysis overlap.
SOFTWARE IMPACTS. Roč. 16, MAY 2023 (2023), č. článku 100498. ISSN 2665-9638
Institucionální podpora: RVO:68081707
Klíčová slova: dna * R-loop * G-quadruplex * Annotation
Obor OECD: Cell biology
Impakt faktor: 2.1, rok: 2022
Způsob publikování: Open access
https://www.sciencedirect.com/science/article/pii/S2665963823000350?via%3Dihub

This contribution puts focus on a command line tool, which enables detection and analysis of overlapping regions between G-quadruplexes, R-loops and genome annotations for selected genomes. G-quadruplexes and R-loops are structures with high Guanine density, which is an important creation factor for both structures. Common regions (overlap) between both structures can provide us with better possibility to create precise model to detect R-loops and valuable insights when inspecting genome annotations with high R-loop density. The tool was used for multiple research projects and is under constant development bringing new features to the world of bioinformatics.
Trvalý link: https://hdl.handle.net/11104/0349900