Catalytic C−C/C−H Bond Activation Relay for Synthesis of Fluorescent Naphthoquinolizinium Salts

0571320 - ÚFCH JH 2024 RIV DE eng J - Článek v odborném periodiku
Ulč, J. - Jacko, J. - Císařová, I. - Pospíšil, Lubomír - Nečas, D. - Kotora, M.
Catalytic C−C/C−H Bond Activation Relay for Synthesis of Fluorescent Naphthoquinolizinium Salts.
European Journal of Organic Chemistry. Roč. 26, č. 18 (2023), č. článku e202300153. ISSN 1434-193X. E-ISSN 1099-0690
Institucionální podpora: RVO:61388955
Klíčová slova: catalysis * C−C activation * C−H activation * fluorescence * heterocycles
Obor OECD: Physical chemistry
Impakt faktor: 2.8, rok: 2022
Způsob publikování: Open access

Herein, we report the design and synthesis of a series of novel cationic nitrogen-embedded polyaromatic hydrocarbons with a planar geometry. The synthetic pathway is based on catalytic C−C/C−H bond activation relay that enabled preparation of regioselectively 5,6,10,11-tetrasubstituted naphtho[2,1,8-ija]quinolizinium salts bearing various types of substituents. Single-crystal X-ray analyses of selected compounds confirmed planarity of the quinolizinium core. Most of the prepared compounds exhibited strong fluorescence (Φs up to >99 %) ranging from 420–600 nm depending on the substitution pattern. According to DFT calculations LUMO is always distributed over the quinolizinium framework regardless of the attached substituents, whereas delocalization of HOMO is related to the substitution pattern. Electrochemical measurements show irreversible reduction of all compounds, which is supported by the calculated location of LUMO orbitals.
Trvalý link: https://hdl.handle.net/11104/0342574