Protein adsorption by nanomechanical mass spectrometry: Beyond the real-time molecular weighting

0569726 - FZÚ 2024 RIV CH eng J - Článek v odborném periodiku
Stachiv, Ivo - Kuo, C.Y. - Li, Wei
Protein adsorption by nanomechanical mass spectrometry: Beyond the real-time molecular weighting.
Frontiers in molecular biosciences. Roč. 9, Jan (2023), č. článku 1058441. E-ISSN 2296-889X
Grant CEP: GA ČR(CZ) GC21-12994J; GA MŠMT(CZ) EF16_019/0000760
Grant ostatní: OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institucionální podpora: RVO:68378271
Klíčová slova: protein adsorption * molecule mechanical properties * molecular weight * protein detection * mass spectrometry * mass sensing
Obor OECD: Condensed matter physics (including formerly solid state physics, supercond.)
Impakt faktor: 5, rok: 2022
Způsob publikování: Open access

During past decades, enormous progress in understanding the mechanisms of the intermolecular interactions between the protein and surface at the single-molecule level has been achieved. These advances could only be possible by the ongoing development of highly sophisticated experimental methods such as atomic force microscopy, optical microscopy, surface plasmon resonance, ellipsometry, quartz crystal microbalance, conventional mass spectrometry, and, more recently, the nanomechanical systems. Here, we highlight the main findings of recent studies on the label-free single-molecule (protein) detection by nanomechanical systems including those focusing on the protein adsorption on various substrate surfaces.
Trvalý link: https://hdl.handle.net/11104/0350599