LDL-C augments whereas HDL-C prevents inflammatory innate immune memory

0569082 - ÚMG 2023 RIV GB eng J - Článek v odborném periodiku
Sohrabi, Yahya - Schwarz, D. - Reinecke, H.
LDL-C augments whereas HDL-C prevents inflammatory innate immune memory.
Trends in Molecular Medicine. Roč. 28, č. 1 (2022), s. 1-4. ISSN 1471-4914. E-ISSN 1471-499X
Institucionální podpora: RVO:68378050
Klíčová slova: atheroslerosis * lipoproteins * cholesterol * inflammation * innate immunity * cardiometabolic diseases
Obor OECD: Biochemistry and molecular biology
Impakt faktor: 13.6, rok: 2022
Způsob publikování: Open access
https://www.sciencedirect.com/science/article/pii/S1471491421003002?via%3Dihub

Recent studies emphasize the importance of low-density lipoprotein cholesterol (LDL-C) in altering the hematopoietic cell compartment of bone marrow and of high-density inhibiting metabolic endotoxemia-induced inflammation. The data suggest that these lipoproteins may exert their inflammatory or anti-inflammatory roles by modulating innate immune memory. HDL-C subfractions could therefore potentially reduce the residual risk in hepatic and cardiometabolic disease.
Trvalý link: https://hdl.handle.net/11104/0340388