Fully soluble polymeric foams for in-vial dried blood spot collection and analysis of acidic drugs by capillary electrophoresis

0566854 - ÚIACH 2024 RIV NL eng J - Článek v odborném periodiku
Ryšavá, Lenka - Dorazilová, J. - Dvořák, Miloš - Sedláček, P. - Vojtová, L. - Kubáň, Pavel
Fully soluble polymeric foams for in-vial dried blood spot collection and analysis of acidic drugs by capillary electrophoresis.
Analytica Chimica Acta. Roč. 1241, FEB (2023), č. článku 340793. ISSN 0003-2670. E-ISSN 1873-4324
Institucionální podpora: RVO:68081715
Klíčová slova: dried blood spots * soluble polymeric foams * automated analysis
Obor OECD: Analytical chemistry
Impakt faktor: 6.2, rok: 2022
Způsob publikování: Omezený přístup

Fully soluble polymeric foams with uniform dimensions (approx. 6 × 3 mm) were developed in this contribution, which were placed in standard capillary electrophoresis vials. The discs were used for in-vial collection of dried blood spots and enabled the direct in-vial DBS processing and at-line analysis by capillary electrophoresis. The concept was demostrated by the direct analysis of non-steroidal antiinflammatory drugs in capillary blood samples.
Trvalý link: https://hdl.handle.net/11104/0338130