Co(II) fenamato, tolfenamato and niflumato complexes with neocuproine: synthesis, crystal structure, spectral characterization and biological activity

0566221 - FZÚ 2024 RIV NL eng J - Článek v odborném periodiku
Smolková, R. - Smolko, L. - Samoľová, Erika - Dušek, Michal
Co(II) fenamato, tolfenamato and niflumato complexes with neocuproine: synthesis, crystal structure, spectral characterization and biological activity.
Journal of Molecular Structure. Roč. 1272, Jan (2023), č. článku 134172. ISSN 0022-2860. E-ISSN 1872-8014
Grant CEP: GA MŠMT(CZ) EF16_019/0000760
Grant ostatní: OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institucionální podpora: RVO:68378271
Klíčová slova: Cobalt(II) complexes * NSAIDs * fenamic acid * tolfenamic acid * fluorescence * DNA-binding
Obor OECD: Condensed matter physics (including formerly solid state physics, supercond.)
Impakt faktor: 3.8, rok: 2022
Způsob publikování: Omezený přístup
https://doi.org/10.1016/j.molstruc.2022.134172

Four novel cobalt(II) complexes with the non-steroidal anti-inflammatory drugs - fenamic acid derivatives have been synthesized and characterized. The complexes [Co(neo)(fen)2] (1) and [Co(neo)(tol)2] (2) were prepared by the reaction of fenamic (Hfen = 2-(phenylamino)benzoic acid) and tolfenamic acid (Htol = 2-[(3-chloro-2-methylphenyl)amino]benzoic acid), respectively with cobalt(II) chloride and neocuproine (neo = 2,9-dimethylphenantroline). However, the same procedure applied to niflumic acid (Hnif = 2-{[3-(trifluoromethyl)phenyl]amino}nicotinic acid) mixture has led to formation of [Co(neo)(nif)2(MeOH)].MeOH (3A) and [CoCl(neo)(nif)(MeOH)] (3B). The crystal structure of all prepared compounds has been determined by single-crystal X-ray crystallography.
Trvalý link: https://hdl.handle.net/11104/0341679