On the possibility to use the charge imbalance in patients undergoing radiotherapy: a new online, in vivo, noninvasive dose monitoring system

0565845 - FZÚ 2023 RIV CH eng J - Článek v odborném periodiku
Cirrone, G. A. P. - Amato, N. - Catalano, R. - Di Domenico, A. - Cuttone, G. - Lojacono, P. - Mazzaglia, A. - Pace, F. - Pitta, G. - Raffaele, L. - Salamone, V. - Spatola, C. - Petringa, Giada
On the possibility to use the charge imbalance in patients undergoing radiotherapy: a new online, in vivo, noninvasive dose monitoring system.
Applied Sciences-Basel. Roč. 11, č. 15 (2021), č. článku 7005. E-ISSN 2076-3417
Institucionální podpora: RVO:68378271
Klíčová slova: in vivo relative dosimetry * proton * radiotherapy * quality controls * beam monitoring
Obor OECD: Particles and field physics
Impakt faktor: 2.838, rok: 2021
Způsob publikování: Open access

A new real-time, in vivo, noninvasive, biasless detector system acting as a beam monitoring and relative dose measurement system. The detector is based on the idea that when a beam current is injected into the body of a patient undergoing a charged particle therapy, the current itself can be collected using a conductive electrode in contact with the patient’s skin. This new approach was studied in vitro using an electrically isolated water tank irradiated with monoenergetic proton beams. The conductive electrode was immersed in water and positioned outside the irradiation field. The detection system performance was evaluated by comparing its response against a SEM detector, used as a reference beam current monitor,and an Advanced Markus ionization chamber. Short-, mid- and long-term reproducibility,current monitoring capability, field size dependence, electrode position and environment temperature dependence, linearity with dose, and dose rate dependence were investigated.

Trvalý link: https://hdl.handle.net/11104/0337363