The intraocular implant and visual rehabilitation improve the quality of life of elderly patients with geographic atrophy secondary to age-related macular degeneration

0562257 - PSÚ 2024 RIV DE eng J - Článek v odborném periodiku
Nekolová, J. - Kremláček, J. - Lukavský, Jiří - Šikl, Radovan - Sin, M. - Langrová, J. - Szanyi, J. - Jirásková, N.
The intraocular implant and visual rehabilitation improve the quality of life of elderly patients with geographic atrophy secondary to age-related macular degeneration.
Graefes Archive for Clinical and Experimental Ophthalmology. Roč. 261, č. 1 (2023), s. 263-272. ISSN 0721-832X. E-ISSN 1435-702X
Institucionální podpora: RVO:68081740
Klíčová slova: Age-related macular degeneration * near vision * quality of life * scharioth macula lens
Obor OECD: Psychology (including human - machine relations)
Impakt faktor: 2.7, rok: 2022
Způsob publikování: Open access
https://link.springer.com/content/pdf/10.1007/s00417-022-05803-6.pdf

Introduction The objective of this prospective study was to evaluate the effects of intraocular macular lens implantation and visual rehabilitation on the quality of life of patients with geographic atrophy (GA) secondary to age-related macular degeneration (AMD). Methods Patients with bilaterally decreased near vision (not better than 0.3 logMAR with the best correction), pseudophakia, were included in the project. The Scharioth macula lens (SML) was implanted into the patients' better-seeing eye. Intensive visual rehabilitation of the ability to perform nearby activities was performed for 20 consecutive postoperative days. All subjects were examined before and after SML implantation ophthalmologically. The National Eye Institute 25-Item Visual Function Questionnaire (NEI VFQ-25) was administered before and 6 months after surgery. Results Twenty eligible patients with mean age 81 years (63 to 92 years) were included in the project: 7 males and 13 females. Nineteen of them completed the 6-month follow-up. Near uncorrected visual acuity was 1.321 +/- 0.208 logMAR before SML implantation and improved to 0.547 +/- 0.210 logMAR after 6 months (dz = - 2.846, p < 0.001, BF10 = 3.29E + 07). In the composite score of the NEI VFQ-25, there was an improvement in the general score and the specific domains related to the implantation. Participants reported fewer difficulties in performing near activities (dz = 0.91, p = 0.001, BF10 = 39.718) and upturns in mental health symptoms related to vision (dz = 0.62, p = .014, BF10 = 3.937). Conclusion SML implantation, followed by appropriate rehabilitation, improved near vision and increased the quality of life of visually handicapped patients with AMD in our project.
Trvalý link: https://hdl.handle.net/11104/0334614