Počet záznamů: 1
African trypanosome strategies for conquering new hosts and territories: the end of monophyly?
- 1.0562196 - BC 2023 RIV GB eng J - Článek v odborném periodiku
Lukeš, Julius - Kachale, Ambar - Votýpka, Jan - Butenko, Anzhelika - Field, Mark Christian
African trypanosome strategies for conquering new hosts and territories: the end of monophyly?
Trends in Parasitology. Roč. 38, č. 9 (2022), s. 724-736. ISSN 1471-4922. E-ISSN 1471-5007
Grant CEP: GA MŠMT(CZ) EF16_019/0000759; GA MŠMT(CZ) LL1601; GA ČR(CZ) GA21-09283S; GA ČR(CZ) GA20-07186S
Institucionální podpora: RVO:60077344
Klíčová slova: African * strategies * territories
Obor OECD: Microbiology
Impakt faktor: 9.6, rok: 2022
Způsob publikování: Omezený přístup
https://www.sciencedirect.com/science/article/pii/S1471492222001143?via%3Dihub
Trypanosoma brucei parasites are the causative agents of African trypanosomiasis in humans, as well as surra, nagana, and dourine in animals. According to current widely used nomenclature, T. brucei is a group of five (sub) species, each causing a distinct disease and possessing unique genetic marker(s) or a combination thereof. However, minimal nuclear genome differences, sometimes accompanied by ongoing genetic exchange, robustly support polyphyly resulting from multiple independent origins of the (sub)species in nature. The ease of generating such (sub)species in the laboratory, as well as the case of overlapping hosts and disease symptoms, is incompatible with the current (sub)species paradigm, which implies a monophyletic origin. Here, we critically re-evaluate this concept, considering recent genome sequencing and experimental studies. We argue that ecotype should be used going forward as a significantly more accurate and appropriate designation.
Trvalý link: https://hdl.handle.net/11104/0339441
Počet záznamů: 1