Mitochondrial ATP synthase of trypanosomes reveals the mechanism of oligomerization and its evolution

0561826 - BC 2023 RIV NL eng A - Abstrakt
Gahura, Ondřej - Muhleip, A. - Hierro Yap, Carolina - Panicucci, Brian - Jain, Minal - Hollaus, D. - Slapničková, Martina - Zíková, Alena - Amunts, A.
Mitochondrial ATP synthase of trypanosomes reveals the mechanism of oligomerization and its evolution.
Biochimica Et Biophysica Acta-Bioenergetics. Elsevier. Roč. 1863 (2022), s. 10-10, č. článku 148628. ISSN 0005-2728. E-ISSN 1879-2650
Institucionální podpora: RVO:60077344
Klíčová slova: Mitochondrial * ATP * trypanosomes
Obor OECD: Biochemistry and molecular biology
https://www.sciencedirect.com/science/article/pii/S0005272822000986

Mitochondrial ATP synthases are multisubunit enzymatic complexes key for energy conversion in most aerobic eukaryotes, forming stable dimers arranged into oligomeric assemblies that are crucial for cristae shaping. Enzymatically, they are reversible nanomotors that can synthesize or hydrolyze ATP, depending on the potential across the inner mitochondrial membrane.
Trvalý link: https://hdl.handle.net/11104/0339046