Time-lapse monitoring of cell mechanical properties

0560916 - FZÚ 2023 RIV CZ eng C - Konferenční příspěvek (zahraniční konf.)
Přibyl, J. - Rotrekl, V. - Pešl, M. - Jelínková, Š. - Kratochvílová, Irena
Time-lapse monitoring of cell mechanical properties.
NANOCON 2020. 12th International Conference on Nanomaterials - Research & Application. Conference proceedings. Ostrava: TANGER, 2021, (2021), s. 416-421. ISBN 978-80-87294-98-7. ISSN 2694-930X.
[International Conference NANOCON 2020 /12./. Brno (CZ), 21.10.2020-23.10.2020]
Institucionální podpora: RVO:68378271
Klíčová slova: atomic force microscopy * mechanical Mapping * cell stiffness * cryopreservation
Obor OECD: Condensed matter physics (including formerly solid state physics, supercond.)
https://www.confer.cz/nanocon/2020/3740-time-lapse-monitoring-of-cell-mechanical-properties

Atomic force microscopy (AFM) is a highly sensitive non-invasive surface method able to provide insight into cells' mechanical parameters. Membrane and sub-membrane development, as well as internal cellular properties, can be monitored. The stiffness of cells is a fundamental phenomenon that reflects changes in cell physiology. More importantly, changes in cell mechanical properties are also often found to be closely associated with various disease conditions. Cell mechanics are mainly dependent on cytoskeletal architecture. The development of cryopreserved cells' mechanical properties (stiffness) after thawing was studied using AFM.

Trvalý link: https://hdl.handle.net/11104/0333693