Co-infection of mammarenaviruses in a wild mouse, Tanzania

0560186 - ÚBO 2023 RIV GB eng J - Článek v odborném periodiku
Cuypers, L. N. - Čížková, Dagmar - Goüy de Bellocq, Joëlle
Co-infection of mammarenaviruses in a wild mouse, Tanzania.
Virus Evolution. Roč. 8, č. 2 (2022), č. článku veac065. E-ISSN 2057-1577
Grant CEP: GA ČR(CZ) GA18-19629S
Výzkumná infrastruktura: e-INFRA CZ - 90140
Institucionální podpora: RVO:68081766
Klíčová slova: co-infection * Mafiga mammarenavirus * Lemniscomys rosalia * zoonotic infections * recombination * BlobTools
Obor OECD: Virology
Impakt faktor: 6.9, rok: 2022
Způsob publikování: Open access
https://academic.oup.com/ve/article/8/2/veac065/6649492?login=true

Mammarenaviruses are bi-segmented RNA viruses. They encompass viruses responsible for several severe diseases in humans. While performing a de novo assembly of a new virus found in a wild single-striped grass mouse in Tanzania, we found a single S but two divergent L segments. Natural co-infections, common within reptarenaviruses in captivity, were never reported for mammarenaviruses and never in a wild sample. This finding can have implications for virus evolution as co-infection could trigger viral recombination/reassortment in natural reservoirs.
Trvalý link: https://hdl.handle.net/11104/0333196