Very long chain fatty acids

0559645 - MBÚ 2023 RIV GB eng J - Článek v odborném periodiku
Kyselová, L. - Vítová, Milada - Řezanka, Tomáš
Very long chain fatty acids.
Progress in Lipid Research. Roč. 87, JUL 2022 (2022), č. článku 101180. ISSN 0163-7827. E-ISSN 1873-2194
Grant CEP: GA ČR(CZ) GA21-07247S
Institucionální podpora: RVO:61388971 ; RVO:67985939
Klíčová slova: performance liquid-chromatographypermeability barrier functionmass-spectrometryamphidinium-carteraegas-chromatographymethyl-estersdipolyunsaturated phosphatidylcholinesrapid identificationmeibomian glandhuman meibum * performance liquid-chromatography * permeability barrier function * mass-spectrometry * amphidinium-carterae * gas-chromatography * methyl-esters * dipolyunsaturated phosphatidylcholines * rapid identification * meibomian glandhuman * meibum
Obor OECD: Microbiology; Analytical chemistry (BU-J)
Impakt faktor: 13.6, rok: 2022
Způsob publikování: Omezený přístup
https://www.sciencedirect.com/science/article/pii/S0163782722000352?via%3Dihub

Very long chain fatty acids (VLCFAs) are important components of various lipid classes in most organisms, from bacteria to higher plants and mammals, including humans. VLCFAs, or very long chain polyunsaturated fatty acids (VLCPUFAs), can be defined as fatty acids with 23 or more carbon atoms in the molecule. The main emphasis in this review is on the analysis of these acids, including obtaining standards from natural sources or their synthesis. Furthermore, the occurrence and analysis of these compounds in both lower (bacteria, invertebrates) and higher organisms (flowering plants or mammals) are discussed in detail. Attention is paid to their biosynthesis, especially the elongation of very long chain fatty acids protein (ELOVL4). This review deals with papers describing these very interesting compounds, whose chemical, biochemical and biological properties have not been fully explored.
Trvalý link: https://hdl.handle.net/11104/0333437