Počet záznamů: 1
Phosphonates and Phosphonate Prodrugs in Medicinal Chemistry: Past Successes and Future Prospects
- 1.0558031 - ÚOCHB 2023 RIV CH eng J - Článek v odborném periodiku
Krečmerová, Marcela - Majer, Pavel - Rais, R. - Slusher, B. S.
Phosphonates and Phosphonate Prodrugs in Medicinal Chemistry: Past Successes and Future Prospects.
Frontiers in Chemistry. Roč. 10, May (2022), č. článku 889737. ISSN 2296-2646. E-ISSN 2296-2646
Grant CEP: GA MŠMT(CZ) LM2018133
Institucionální podpora: RVO:61388963
Klíčová slova: acyclic nucleoside phosphonates * antivirals * prodrugs * protides * GCPII * prostate-specific membrane antigen * FOLH1 * 2-PMPA
Obor OECD: Organic chemistry
Impakt faktor: 5.5, rok: 2022
Způsob publikování: Open access
https://doi.org/10.3389/fchem.2022.889737
The review focus on biologically active phosphonates that originated from the IOCB Prague, i.e. acyclic nucleoside phosphonates, and derivatives of non-nucleoside phosphonates such as 2-(phosphonomethyl) pentanedioic acid (2-PMPA). Principal strategies of their syntheses and modifications to prodrugs is reported.
Trvalý link: http://hdl.handle.net/11104/0331849
Počet záznamů: 1