Metabolism of Aldoximes and Nitriles in Plant-Associated Bacteria and Its Potential in Plant-Bacteria Interactions

0556541 - MBÚ 2023 RIV CH eng J - Článek v odborném periodiku
Rädisch, Robert - Pátek, Miroslav - Křístková, Barbora - Winkler, M. - Křen, Vladimír - Martínková, Ludmila
Metabolism of Aldoximes and Nitriles in Plant-Associated Bacteria and Its Potential in Plant-Bacteria Interactions.
Microorganisms. Roč. 10, č. 3 (2022), č. článku 549. E-ISSN 2076-2607
Grant CEP: GA ČR(CZ) GF20-23532L
Institucionální podpora: RVO:61388971
Klíčová slova: pseudomonas-chlororaphis b23 * heme-containing lyase * sp strain oxb-1 * bacillus sp * phenylacetaldoxime dehydratase * biochemical-characterization * heterologous expression * gene cloning * purification * hydratase * plant aldoxime * aldoxime-nitrile pathway * plant defense * phytohormone * indole-3-acetic acid * aldoxime dehydratase * nitrilase * nitrile hydratase * plant-bacteria interaction
Obor OECD: Biochemistry and molecular biology
Impakt faktor: 4.5, rok: 2022
Způsob publikování: Open access
https://www.mdpi.com/2076-2607/10/3/549/htm

In plants, aldoximes per se act as defense compounds and are precursors of complex defense compounds such as cyanogenic glucosides and glucosinolates. Bacteria rarely produce aldoximes, but some are able to transform them by aldoxime dehydratase (Oxd), followed by nitrilase (NLase) or nitrile hydratase (NHase) catalyzed transformations. Oxds are often encoded together with NLases or NHases in a single operon, forming the aldoxime-nitrile pathway. Previous reviews have largely focused on the use of Oxds and NLases or NHases in organic synthesis. In contrast, the focus of this review is on the contribution of these enzymes to plant-bacteria interactions. Therefore, we summarize the substrate specificities of the enzymes for plant compounds. We also analyze the taxonomic and ecological distribution of the enzymes. In addition, we discuss their importance in selected plant symbionts. The data show that Oxds, NLases, and NHases are abundant in Actinobacteria and Proteobacteria. The enzymes seem to be important for breaking through plant defenses and utilizing oximes or nitriles as nutrients. They may also contribute, e.g., to the synthesis of the phytohormone indole-3-acetic acid. We conclude that the bacterial and plant metabolism of aldoximes and nitriles may interfere in several ways. However, further in vitro and in vivo studies are needed to better understand this underexplored aspect of plant-bacteria interactions.
Trvalý link: http://hdl.handle.net/11104/0331548