Počet záznamů: 1
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts
- 1.0555733 - ÚMG 2022 RIV US eng J - Článek v odborném periodiku
Woo, X. - Sedláček, Radislav - Chuang, J.H. … celkem 64 autorů
Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts.
Nature Genetics. Roč. 53, č. 1 (2021), s. 86-99. ISSN 1061-4036. E-ISSN 1546-1718
Institucionální podpora: RVO:68378050
Klíčová slova: tumor xenografts * mouse models * breast * heterogeneity * aberrations * signatures * evolution * cells * architecture * metastasis
Obor OECD: Oncology
Impakt faktor: 41.376, rok: 2021
Způsob publikování: Open access
https://www.nature.com/articles/s41588-020-00750-6
Analysis of copy number alterations in 1,451 patient-derived xenografts (PDXs) and matched patient tumor samples shows strong conservation from patient tumors through late-passage PDXs and a lack of systematic copy number evolution driven by the mouse host.
Trvalý link: http://hdl.handle.net/11104/0330189
Počet záznamů: 1