Počet záznamů: 1
Nematicidal activity of naphthalimide-boron cluster conjugates
- 1.0553327 - ÚACH 2023 RIV GB eng J - Článek v odborném periodiku
Bogucka-Kocka, A. - Kolodziej, P. - Makuch-Kocka, A. - Rozycka, D. - Rykowski, S. - Nekvinda, Jan - Grüner, Bohumír - Olejniczak, A.
Nematicidal activity of naphthalimide-boron cluster conjugates.
Chemical Communications. Roč. 58, č. 15 (2022), s. 2528-2531. ISSN 1359-7345. E-ISSN 1364-548X
Grant CEP: GA ČR(CZ) GA21-14409S
Institucionální podpora: RVO:61388980
Klíčová slova: in-vitro * drug * anticancer * albendazole * mebendazole * pharmacophores * lipophilicity * resistance
Obor OECD: Inorganic and nuclear chemistry
Impakt faktor: 4.9, rok: 2022
Způsob publikování: Omezený přístup
https://doi.org/10.1039/D1CC07075D
This study presents the activity of a series of 1,8-naphthalimide-carborane/metallacarborane conjugates against Rhabditis sp. The carborane conjugates were the least active. Selected conjugates with cobaltacarborane (5 and 6) showed high activity. Their lethal concentration (LC50) values are substantially lower than that of the drug mebendazole.
Trvalý link: http://hdl.handle.net/11104/0328285
Počet záznamů: 1