Synergistic performance of collagen-g-chitosan-glucan fiber biohybrid scaffold with tunable properties

0553177 - ÚMCH 2023 RIV GB eng J - Článek v odborném periodiku
Abdel-Rahman, Rasha M. - Vishakha, V. - Kelnar, Ivan - Jancar, J. - Abdel-Mohsen, Abdellatif M.
Synergistic performance of collagen-g-chitosan-glucan fiber biohybrid scaffold with tunable properties.
International Journal of Biological Macromolecules. Roč. 202, 31 March (2022), s. 671-680. ISSN 0141-8130. E-ISSN 1879-0003
Grant CEP: GA ČR(CZ) GA19-06065S
Institucionální podpora: RVO:61389013
Klíčová slova: hybrid scaffolds * collagen * chitosan-glucan fiber
Obor OECD: Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics
Impakt faktor: 8.2, rok: 2022
Způsob publikování: Omezený přístup
https://www.sciencedirect.com/science/article/pii/S0141813022000058?via%3Dihub

Hybrid biocomposite scaffolds (HBS) that serve as a carrier for cell proliferation and differentiation are increasingly used for tissue regeneration. 3D hybrid scaffold based on collagen-grafted-chitosan-glucan fiber (CO-g-CGF-HBS) was prepared by freeze-drying technique. The swelling percentage, hydrolytic stability, and modulus of elasticity of HBS were enhanced after the chemical modification of CO with CGF. Pore size and porosity of HBS were decreased with an increased CGF ratio. HBS exhibits a higher reduction rate against different types of bacteria compared with a control sample. Thus, chemical modification of CO with different ratios of CGF significantly improved the physicochemical, antibacterial properties of HBS.
Trvalý link: http://hdl.handle.net/11104/0328447