The cnidarian parasite Ceratonova shasta utilizes inherited and recruited venom-like compounds during infection

0551122 - BC 2022 RIV US eng J - Článek v odborném periodiku
Americus, B. - Hams, N. - Klompen, A. - Alama-Bermejo, Gema - Lotan, T. - Bartholomew, J. - Atkinson, S.
The cnidarian parasite Ceratonova shasta utilizes inherited and recruited venom-like compounds during infection.
PeerJ. Roč. 9, DEC 15 2021 (2021), č. článku e12606. ISSN 2167-8359. E-ISSN 2167-8359
Institucionální podpora: RVO:60077344
Klíčová slova: protein * nematocyst * diversity * evolution * myxozoa * metalloproteinases * transcriptome * adaptations * mechanisms * scyphozoan * Toxin * Venom * Myxozoa * Cnidaria * Nematocyst * Proteome * Transcriptome * Myxospore
Obor OECD: Genetics and heredity (medical genetics to be 3)
Impakt faktor: 3.061, rok: 2021
Způsob publikování: Open access
https://peerj.com/articles/12606/

Background: Cnidarians are the most ancient venomous organisms. They store a cocktail of venom proteins inside unique stinging organelles called nematocysts. When a cnidarian encounters chemical and physical cues from a potential threat or prey animal, the nematocyst is triggered and fires a harpoon-like tubule to penetrate and inject venom into the prey. Nematocysts are present in all Cnidaria, including the morphologically simple Myxozoa, which are a speciose group of microscopic, spore-forming, obligate parasites of fish and invertebrates. Rather than predation or defense, myxozoans use nematocysts for adhesion to hosts, but the involvement of venom in this process is poorly understood. Recent work shows some myxozoans have a reduced repertoire of venom-like compounds (VLCs) relative to free-living cnidarians, however the function of these proteins is not known.
Trvalý link: http://hdl.handle.net/11104/0326937