Počet záznamů: 1
Long Non-Coding RNAs and Their Potential Roles in the Vector-Host-Pathogen Triad
- 1.0549064 - BC 2022 RIV CH eng J - Článek v odborném periodiku
Ahmad, Parwez - Bensaoud, Chaima - Mekki, Imen - Rehman, M.U. - Kotsyfakis, Michalis
Long Non-Coding RNAs and Their Potential Roles in the Vector-Host-Pathogen Triad.
Life. Roč. 11, č. 1 (2021), č. článku 56. E-ISSN 2075-1729
Grant CEP: GA ČR(CZ) GA19-07247S; GA MŠMT(CZ) EF16_019/0000759; GA MŠMT(CZ) EF20_079/0017809
Institucionální podpora: RVO:60077344
Klíčová slova: ncRNA * lncRNA * vector * host * pathogen interactions
Obor OECD: Microbiology
Impakt faktor: 3.253, rok: 2021
Způsob publikování: Open access
https://www.mdpi.com/2075-1729/11/1/56
Long non-coding (lnc)RNAs have emerged as critical regulators of gene expression and are involved in almost every cellular process. They can bind to other molecules including DNA, proteins, or even other RNA types such messenger RNA or small RNAs. LncRNAs are typically expressed at much lower levels than mRNA, and their expression is often restricted to tissue- or time-specific developmental stages. They are also involved in several inter-species interactions, including vector-host-pathogen interactions, where they can be either vector/host-derived or encoded by pathogens. In these interactions, they function via multiple mechanisms including regulating pathogen growth and replication or via cell-autonomous antimicrobial defense mechanisms. Recent advances suggest that characterizing lncRNAs and their targets in different species may hold the key to understanding the role of this class of non-coding RNA in interspecies crosstalk. In this review, we present a general overview of recent studies related to lncRNA-related regulation of gene expression as well as their possible involvement in regulating vector-host-pathogen interactions.
Trvalý link: http://hdl.handle.net/11104/0325094
Počet záznamů: 1