Bimetallic nanowires on laser-patterned PEN as promising biomaterials

0547750 - BC 2022 RIV CH eng J - Článek v odborném periodiku
Pryjmaková, J. - Kaimlová, M. - Vokatá, B. - Hubáček, Tomáš - Slepička, P. - Svorčík, V. - Siegel, J.
Bimetallic nanowires on laser-patterned PEN as promising biomaterials.
Nanomaterials. Roč. 11, č. 9 (2021), č. článku 2285. E-ISSN 2079-4991
Institucionální podpora: RVO:60077344
Klíčová slova: surface modification * nanostructure * polymer * bimetallic nanowires * biocompatibility * antibacterial properties
Obor OECD: Materials engineering
Impakt faktor: 5.719, rok: 2021
Způsob publikování: Open access
https://www.mdpi.com/2079-4991/11/9/2285

As inflammation frequently occurs after the implantation of a medical device, biocompatible, antibacterial materials must be used. Polymer-metal nanocomposites are promising materials. Here we prepared enhanced polyethylene naphthalate (PEN) using surface modification techniques and investigated its suitability for biomedical applications. The PEN was modified by a KrF laser forming periodic ripple patterns with specific surface characteristics. Next, Au/Ag nanowires were deposited onto the patterned PEN using vacuum evaporation. Atomic force microscopy confirmed that the surface morphology of the modified PEN changed accordingly with the incidence angle of the laser beam. Energy-dispersive X-ray spectroscopy showed that the distribution of the selected metals was dependent on the evaporation technique. Our bimetallic nanowires appear to be promising antibacterial agents due to the presence of antibacterial noble metals. The antibacterial effect of the prepared Au/Ag nanowires against E. coli and S. epidermidis was demonstrated using 24 h incubation with a drop plate test. Moreover, a WST-1 cytotoxicity test that was performed to determine the toxicity of the nanowires showed that the materials could be considered non-toxic. Collectively, these results suggest that prepared Au/Ag nanostructures are effective, biocompatible surface coatings for use in medical devices.
Trvalý link: http://hdl.handle.net/11104/0324812