Microstructural, mechanical, in vitro corrosion and biological characterization of an extruded Zn-0.8Mg-0.2Sr (wt%) as an absorbable material

0546345 - FZÚ 2022 RIV CH eng J - Článek v odborném periodiku
Čapek, Jaroslav - Kubásek, J. - Pinc, Jan - Fojt, J. - Krajewski, S. - Rupp, F. - Li, P.
Microstructural, mechanical, in vitro corrosion and biological characterization of an extruded Zn-0.8Mg-0.2Sr (wt%) as an absorbable material.
Materials Science & Engineering C-Materials for Biological Applications. Roč. 122, Mar. (2021), č. článku 111924. ISSN 0928-4931. E-ISSN 1873-0191
Grant CEP: GA MŠMT(CZ) EF16_019/0000760; GA ČR(CZ) GA18-06110S
Grant ostatní: OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institucionální podpora: RVO:68378271
Klíčová slova: absorbable metals * zinc * mechanical properties * degradation behaviour * cytotoxicity * antibacterial property
Obor OECD: Materials engineering
Impakt faktor: 8.457, rok: 2021
Způsob publikování: Open access

In the presented study, a novel Zn-0.8Mg-0.2Sr (wt%) alloy has been fabricated by the combination of casting, homogenization annealing and extrusion at 200 °C. The prepared material is characterized by an excellent combination of tensile yield strength, ultimate tensile strength and elongation corresponding to 244 MPa, 324 MPa and 20% respectively. The in vitro corrosion rates of the Zn-0.8Mg-0.2Sr alloy in the physiological solution and the simulated body fluid were 244 μm/a and 69.8 μm/a, respectively. Furthermore, an extract test revealed that Zn-0.8Mg-0.2Sr extracts diluted to 25% had no adverse effects towards L929 fibroblasts, TAg periosteal cells and Saos-2 osteoblasts. Moreover, the Zn-0.8Mg-0.2Sr surface showed effective inhibition of initial Streptococcus gordonii adhesion and biofilm formation. These results indicated the Zn-0.8Mg-0.2Sr alloy, which has superior mechanical properties, might be a promising candidate for materials used for load-bearing applications.
Trvalý link: http://hdl.handle.net/11104/0322883