Differential subcellular distribution of cytokinins: How does membrane transport fit into the big picture?

0545919 - ÚEB 2022 RIV CH eng J - Článek v odborném periodiku
Nedvěd, Daniel - Hošek, Petr - Klíma, Petr - Hoyerová, Klára
Differential subcellular distribution of cytokinins: How does membrane transport fit into the big picture?
International Journal of Molecular Sciences. Roč. 22, č. 7 (2021), č. článku 3428. E-ISSN 1422-0067
Grant CEP: GA MŠMT(CZ) EF16_019/0000738
Institucionální podpora: RVO:61389030
Klíčová slova: Cytokinin distribution * Cytokinin hydrophobicity * Cytokinin transport * Membrane transport * pup14
Obor OECD: Biochemical research methods
Impakt faktor: 6.208, rok: 2021
Způsob publikování: Open access
http://doi.org/10.3390/ijms22073428

Cytokinins are a class of phytohormones, signalling molecules specific to plants. They act as regulators of diverse physiological processes in complex signalling pathways. It is necessary for plants to continuously regulate cytokinin distribution among different organs, tissues, cells, and com-partments. Such regulatory mechanisms include cytokinin biosynthesis, metabolic conversions and degradation, as well as cytokinin membrane transport. In our review, we aim to provide a thorough picture of the latter. We begin by summarizing cytokinin structures and physicochemical properties. Then, we revise the elementary thermodynamic and kinetic aspects of cytokinin membrane transport. Next, we review which membrane-bound carrier proteins and protein families recognize cytokinins as their substrates. Namely, we discuss the families of “equilibrative nucleoside transporters” and “purine permeases”, which translocate diverse purine-related compounds, and proteins AtPUP14, AtABCG14, AtAZG1, and AtAZG2, which are specific to cytokinins. We also address long-distance cytokinin transport. Putting all these pieces together, we finally discuss cytokinin distribution as a net result of these processes, diverse in their physicochemical nature but acting together to promote plant fitness.
Trvalý link: http://hdl.handle.net/11104/0322528