Plasmalogens - Ubiquitous molecules occurring widely, from anaerobic bacteria to humans

0545667 - MBÚ 2022 RIV GB eng J - Článek v odborném periodiku
Vítová, Milada - Palyzová, Andrea - Řezanka, Tomáš
Plasmalogens - Ubiquitous molecules occurring widely, from anaerobic bacteria to humans.
Progress in Lipid Research. Roč. 83, JUL 2021 (2021), č. článku 101111. ISSN 0163-7827. E-ISSN 1873-2194
GRANT EU: European Commission(CZ) ATCZ172 - Interreg V-A Austria – Czech Republic; European Commission Interreg, REEgain
Institucionální podpora: RVO:61388971
Klíčová slova: performance liquid-chromatography * hydrophilic interaction chromatography * hexagonal phase-transition * trap mass-spectrometry * volatile fatty acids * clostridium-butyricum * ether lipids * ethanolamine plasmalogens * metabolic function * growth factors
Obor OECD: Microbiology
Impakt faktor: 14.673, rok: 2021
Způsob publikování: Omezený přístup
https://www.sciencedirect.com/science/article/pii/S0163782721000278?via%3Dihub

Plasmalogens are a group of lipids mainly found in the cell membranes. They occur in anaerobic bacteria and in some protozoa, invertebrates and vertebrates, including humans. Their occurrence in plants and fungi is controversial. They can protect cells from damage by reactive oxygen species, protect other phospholipids or lipoprotein particles against oxidative stress, and have been implicated as signaling molecules and modulators of membrane dynamics. Biosynthesis in anaerobic and aerobic organisms occurs by different pathways, and the main biosynthetic pathway in anaerobic bacteria was clarified only this year (2021). Many different analytical techniques have been used for plasmalogen analysis, some of which are detailed below. These can be divided into two groups: shotgun lipidomics, or electrospray ionization mass spectrometry in combination with high performance liquid chromatography (LC-MS). The advantages and limitations of both techniques are discussed here, using examples from anaerobic bacteria to specialized mammalian (human) organs.
Trvalý link: http://hdl.handle.net/11104/0322336