Apoptotic induction in K562 cell line by new water-soluble complexes of nickel(II) and zinc(II)

0543047 - FZÚ 2022 RIV GB eng J - Článek v odborném periodiku
Mirzaahmadi, A. - Hosseini-Yazdi, S.A. - Mahdavi, M. - Dušek, Michal - Eigner, Václav - Poupon, Morgane
Apoptotic induction in K562 cell line by new water-soluble complexes of nickel(II) and zinc(II).
Polyhedron. Roč. 202, July (2021), č. článku 115205. ISSN 0277-5387. E-ISSN 1873-3719
Grant CEP: GA ČR(CZ) GA18-10504S; GA MŠMT LM2018110
Institucionální podpora: RVO:68378271
Klíčová slova: apoptosis * cell cycle * ctotoxicity * cytotoxicity * flow cytometry * water-soluble thiosemicarbazone * crystal structure
Obor OECD: Condensed matter physics (including formerly solid state physics, supercond.)
Impakt faktor: 2.975, rok: 2021
Způsob publikování: Omezený přístup
https://doi.org/10.1016/j.poly.2021.115205

New water-soluble Zn(II) and Ni(II) complexes with three thiosemicarbazone ligands, modified by substitution (H, Me, Ph), H2L1Cl, H2L2Cl and H2L3Cl were synthesized through the reaction of the ligands with chloride salts of metals. All complexes were characterized by physico-chemical techniques. Elemental analysis and X-ray crystallography confirmed that metal to ligand ratio 1:2 in nickel(II) complexes and 1:1 in zinc(II) complexes.
Trvalý link: http://hdl.handle.net/11104/0320355