Počet záznamů: 1
Catalase and Ascorbate Peroxidase in Euglenozoan Protists
- 1.0540625 - BC 2021 RIV CH eng J - Článek v odborném periodiku
Škodová-Sveráková, Ingrid - Záhonová, Kristýna - Bučková, B. - Füssy, Z. - Yurchenko, V. - Lukeš, Julius
Catalase and Ascorbate Peroxidase in Euglenozoan Protists.
Pathogens. Roč. 9, č. 4 (2020), č. článku 317. E-ISSN 2076-0817
Grant CEP: GA MŠMT(CZ) LL1601; GA ČR(CZ) GA18-15962S; GA ČR(CZ) GA20-07186S; GA MŠMT(CZ) EF16_019/0000759
Institucionální podpora: RVO:60077344
Klíčová slova: hydrogen-peroxide * glutathione-reductase * oxidative stress * leishmania-major * tobacco plants * gene family * metabolism * trypanothione * prediction * antioxidants * Euglenozoa * ascorbate peroxidase * catalase * enzymatic activity * phylogeny
Obor OECD: Microbiology
Impakt faktor: 3.492, rok: 2020
Způsob publikování: Open access
https://www.mdpi.com/2076-0817/9/4/317
In this work, we studied the biochemical properties and evolutionary histories of catalase (CAT) and ascorbate peroxidase (APX), two central enzymes of reactive oxygen species detoxification, across the highly diverse clade Eugenozoa. This clade encompasses free-living phototrophic and heterotrophic flagellates, as well as obligate parasites of insects, vertebrates, and plants. We present evidence of several independent acquisitions of CAT by horizontal gene transfers and evolutionary novelties associated with the APX presence. We posit that Euglenozoa recruit these detoxifying enzymes for specific molecular tasks, such as photosynthesis in euglenids and membrane-bound peroxidase activity in kinetoplastids and some diplonemids.
Trvalý link: http://hdl.handle.net/11104/0318246
Počet záznamů: 1