Nanoparticles in human life: friends or foes?

0540554 - ÚEM 2021 RIV CZ eng M - Část monografie knihy
Zajícová, Alena
The Use of Nanofiber Scaffolds for the Transfer of Stem Cellls for the Treatment of Damaged Ocular Surface.
Nanoparticles in human life: friends or foes? Praha 3: Proxima Tisk s.r.o., 2020 - (David, L.), s. 79-86. ISBN 978-80-906655-9-0
Grant CEP: GA MŠMT(CZ) LO1508
Institucionální podpora: RVO:68378041
Klíčová slova: mesenchymal stem cells * corneal injuries * nanofiber scaffolds * stem cell transplantation
Obor OECD: Genetics and heredity (medical genetics to be 3)

If the corneal damage is very extensive and the limbal stem cell (LSC) region is involved, it can lead to LSC defficiency. The only way to treat LSC defficiency is transplantation of stem cells. To fix stem cells onto the ocular surface, various types of carriers have been tested. Promising scaffolds for growth and transfer of stem cells have been provided by nanotechnology. To produce nanofibers, the electrospinning technology was used. The great advantage of this technique is the possibility to define the properties of nanofiber scaffolds, optimal for growth and transfer of stem cells.


Trvalý link: http://hdl.handle.net/11104/0318349