0538927 - ÚEB 2021 RIV CH eng J - Článek v odborném periodiku
Abdollahi Sisi, Nayyer - Růžička, Kamil
Er-localized pin carriers: Regulators of intracellular auxin homeostasis.
Plants. Roč. 9, č. 11 (2020), s. 1-10, č. článku 1527. E-ISSN 2223-7747
Grant CEP: GA ČR(CZ) GA19-23773S; GA MŠMT(CZ) LTC18073; GA MŠMT(CZ) EF16_019/0000738
Institucionální podpora: RVO:61389030
Klíčová slova: Auxin metabolism * Auxin transport * ER-PINs * PIN proteins * pin5 * pin8
Obor OECD: Plant sciences, botany
Impakt faktor: 3.935, rok: 2020
Způsob publikování: Open access
http://doi.org/10.3390/plants9111527

The proper distribution of the hormone auxin is essential for plant development. It is channeled by auxin efflux carriers of the PIN family, typically asymmetrically located on the plasma membrane (PM). Several studies demonstrated that some PIN transporters are also located at the endoplasmic reticulum (ER). From the PM-PINs, they differ in a shorter internal hydrophilic loop, which carries the most important structural features required for their subcellular localization, but their biological role is otherwise relatively poorly known. We discuss how ER-PINs take part in maintaining intracellular auxin homeostasis, possibly by modulating the internal levels of IAA, it seems that the exact identity of the metabolites downstream of ER-PINs is not entirely clear as well. We further review the current knowledge about their predicted structure, evolution and localization. Finally, we also summarize their role in plant development.
Trvalý link: http://hdl.handle.net/11104/0316666