Mitogenomics of the endemic Ethiopian rats: looking for footprints of adaptive evolution in sky islands

0538392 - ÚBO 2022 RIV NL eng J - Článek v odborném periodiku
Bartáková, Veronika - Bryjová, Anna - Nicolas, V. - Lavrenchenko, L. A. - Bryja, Josef
Mitogenomics of the endemic Ethiopian rats: looking for footprints of adaptive evolution in sky islands.
Mitochondrion. Roč. 57, March (2021), s. 182-191. ISSN 1567-7249. E-ISSN 1872-8278
Grant CEP: GA ČR(CZ) GA18-17398S
Institucionální podpora: RVO:68081766
Klíčová slova: adaptation * NADH dehydrogenase * adaptive introgression * dN/dS * oxidative phosphorylation * positive selection
Obor OECD: Zoology
Impakt faktor: 4.534, rok: 2021
Způsob publikování: Omezený přístup
https://www.sciencedirect.com/science/article/pii/S1567724920302464?via%3Dihub

Organisms living in high altitude must adapt to environmental conditions with hypoxia and low temperature, e.g. by changes in the structure and function of proteins associated with oxidative phosphorylation in mitochondria. Here we analysed the signs of adaptive evolution in 27 mitogenomes of endemic Ethiopian rats (Stenocephalemys), where individual species adapted to different elevation. Significant signals of positive selection were detected in 10 of the 13 mitochondrial protein-coding genes, with a majority of functional substitutions in the NADH dehydrogenase complex. Higher frequency of positively selected sites was found in phylogenetic lineages corresponding to Afroalpine specialists.
Trvalý link: http://hdl.handle.net/11104/0316205