Diverse alveolate infections of tadpoles, a new threat to frogs?

0538253 - BC 2021 RIV US eng J - Článek v odborném periodiku
Chambouvet, A. - Smilansky, V. - Jirků, Miloslav - Isidoro-Ayza, M. - Itoiz, S. - Derelle, E. - Monier, A. - Gower, D.J. - Wilkinson, M. - Yabsley, M. J. - Lukeš, Julius - Richards, T.A.
Diverse alveolate infections of tadpoles, a new threat to frogs?
PLoS Pathogens. Roč. 16, č. 2 (2020), č. článku e1008107. ISSN 1553-7366. E-ISSN 1553-7374
Grant CEP: GA MŠMT(CZ) EF16_019/0000759
Institucionální podpora: RVO:60077344
Klíčová slova: lethal chytridiomycosis * apicomplexa
Obor OECD: Microbiology
Impakt faktor: 6.823, rok: 2020
Způsob publikování: Open access
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1008107

The research summarized here demonstrates a range of alveolate infections of specific tadpole tissues and cell types critical for immune function and core physiology. The severe Perkinsozoa-infection etiologic agent associated with mass mortality events across the USA is now considered an emerging infection [16] and lies within a particular alveolate clade sampled from freshwater environments and tadpole tissues. We need to know how deterministic these infections are, either individually or in concert with other microbes and/or environmental factors, and the epizootiology of the disease. For example, environmental factors, such as pollution, can create sublethal stress resulting in suppression of the immune function, leading to an increase of disease susceptibility. As such, we need to apply an approach that allows the investigation of disease progression concordant with formal tests of Koch’s postulates [7]. We also need to know how virulence, if present, varies among different amphibian-associated perkinsozoans and apicomplexans.
Trvalý link: http://hdl.handle.net/11104/0316082