Translational Research in Serious Human Diseases

0536489 - ÚŽFG 2021 RIV CZ eng M - Část monografie knihy
Baxa, Monika
Motor, cognitive, and behavioral tests conducted in pigs.
Translational Research in Serious Human Diseases. Praha: Academia, 2020 - (Kello, M.; Strnadel, J.; Klempir, J.; Roth, J.; Myslivcová-Fučíková, A.; Hansíková, H.; Kozák, I.), s. 30-36. ISBN 978-80-200-3158-7
Grant CEP: GA MŠMT(CZ) LO1609
Institucionální podpora: RVO:67985904
Klíčová slova: pig * biomedicine * motor
Obor OECD: Behavioral sciences biology

Pigs have been widely used for modelling various motor, cognitive or behavioural diseases. The more the model simulates the symptoms of the disease, the better it is for the evaluation of the safety and efficacy of potential therapeutic treatments. Therefore, investigation of the tests for monitoring the disease manifestation and evaluation of safety and efficacy of potential therapies arose on the scene. Phenotyping varies in battery of tests that measure behavioural changes as well as changes in motor and cognitive functions. Technological progress enables the use of objective electronic devices and thus eliminates the subjective feature of data collection and evaluation.
Trvalý link: http://hdl.handle.net/11104/0314262