Počet záznamů: 1
Synthesis, characterisation and supercritical fluid chromatography enantioseparation of new liquid crystalline materials
- 1.0536056 - FZÚ 2021 RIV GB eng J - Článek v odborném periodiku
Urbańska, M. - Vaňkátová, Petra - Kubíčková, A. - Kalíková, K.
Synthesis, characterisation and supercritical fluid chromatography enantioseparation of new liquid crystalline materials.
Liquid Crystals. Roč. 47, č. 12 (2020), s. 1832-1843. ISSN 0267-8292. E-ISSN 1366-5855
Institucionální podpora: RVO:68378271
Klíčová slova: liquid crystal * synthesis * racemic mixtures * enantioseparation * supercritical fluid chromatography
Obor OECD: Analytical chemistry
Impakt faktor: 2.908, rok: 2019
Způsob publikování: Omezený přístup
https://doi.org/10.1080/02678292.2020.1733684
Enantiomeric excess (EE) highly affects the mesomorphic properties of mesogens containing centre of chirality. Thus, there is need of methods for evaluation of the EE of newly synthesised compounds as it should be considered when discussing the mesomorphic properties. We report synthesis and characterisation of ten new racemic mixtures based on (R,S)-3-octanol, which were used to develop an enantioseparation method that can be used for the assessment of the EE of chiral liquid crystals and their mixtures. The mesomorphic properties of novel materials were measured. Supercritical fluid chromatography with polysaccharide-based chiral stationary phases was used to develop reliable method for enantioseparation of the materials. A complete separation of (S) and (R) enantiomers with resolution values higher than 2.0 was obtained for all materials using simple mobile phase. The enantiomer elution order was assessed using pure (S) enantiomers of all materials. For all materials (R) enantiomer elutes first which is advantageous for use as optical purity control of newly synthesised (S) enantiomers.
Trvalý link: http://hdl.handle.net/11104/0313907
Počet záznamů: 1