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Effect of static magnetic field on DNA synthesis: the interplay between DNA chirality and magnetic field left‐right asymmetry
- 1.0533093 - FZÚ 2021 RIV US eng J - Článek v odborném periodiku
Yang, X. - Li, Z. - Polyakova, Tetyana - Dejneka, Alexandr - Zablotskyy, Vitaliy A. - Zhang, X.
Effect of static magnetic field on DNA synthesis: the interplay between DNA chirality and magnetic field left‐right asymmetry.
FASEB BioAdvances. Roč. 2, č. 4 (2020), s. 254-263. ISSN 2573-9832
Grant CEP: GA MŠMT(CZ) EF16_019/0000760
Grant ostatní: OP VVV - SOLID21(XE) CZ.02.1.01/0.0/0.0/16_019/0000760
Institucionální podpora: RVO:68378271
Klíčová slova: biomagnetic effects * DNA synthesis * homochirality * left-right asymmetry * magnetic field
Obor OECD: Condensed matter physics (including formerly solid state physics, supercond.)
Způsob publikování: Open access
Interactions between magnetic fields (MFs) and living cells may stimulate a large variety of cellular responses to a MF, while the underlying intracellular mechanisms still remain a great puzzle. On a fundamental level, the MF — cell interaction is affected by the two broken symmetries: (a) left‐right (LR) asymmetry of the MF and (b) chirality of DNA molecules carrying electric charges and subjected to the Lorentz force when moving in a MF. Here we report on the chirality‐driven effect of static magnetic fields (SMFs) on DNA synthesis. This newly discovered effect reveals how the interplay between two fundamental features of symmetry in living and inanimate nature—DNA chirality and the inherent features of MFs to distinguish the left and right—manifests itself in different DNA synthesis rates in the upward and downward SMFs, consequently resulting in unequal cell proliferation for the two directions of the field.
Trvalý link: http://hdl.handle.net/11104/0311581
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