Nanoscale Dynamic Readout of a Chemical Redox Process Using Radicals Coupled with Nitrogen-Vacancy Centers in Nanodiamonds

0533052 - ÚOCHB 2021 RIV US eng J - Článek v odborném periodiku
Bartoň, Jan - Gulka, M. - Tarábek, Ján - Mindarava, Y. - Wang, Z. - Schimer, Jiří - Raabová, Helena - Bednár, J. - Plenio, M. B. - Jelezko, F. - Nesladek, M. - Cígler, Petr
Nanoscale Dynamic Readout of a Chemical Redox Process Using Radicals Coupled with Nitrogen-Vacancy Centers in Nanodiamonds.
ACS Nano. Roč. 14, č. 10 (2020), s. 12938-12950. ISSN 1936-0851. E-ISSN 1936-086X
Grant CEP: GA ČR(CZ) GA18-17071S; GA MŠMT 8C18004; GA MŠMT(CZ) EF16_019/0000729; GA MŠMT EF16_026/0008382
Institucionální podpora: RVO:61388963
Klíčová slova: quantum sensing * nanodiamond * nitrogen-vacancy center * radical * chemical reaction * T1 spin relaxation time
Obor OECD: Physical chemistry
Impakt faktor: 15.881, rok: 2020
Způsob publikování: Omezený přístup
https://doi.org/10.1021/acsnano.0c04010

Biocompatible nanoscale probes for sensitive detection of paramagnetic species and molecules associated with their (bio)chemical transformations would provide a desirable tool for a better understanding of cellular redox processes. Here, we describe an analytical tool based on quantum sensing techniques. We magnetically coupled negatively charged nitrogen-vacancy (NV) centers in nanodiamonds (NDs) with nitroxide radicals present in a bioinert polymer coating of the NDs. We demonstrated that the T1 spin relaxation time of the NV centers is very sensitive to the number of nitroxide radicals, with a resolution down to ∼10 spins per ND (detection of approximately 10–23 mol in a localized volume). The detection is based on T1 shortening upon the radical attachment, and we propose a theoretical model describing this phenomenon. We further show that this colloidally stable, water-soluble system can be used dynamically for spatiotemporal readout of a redox chemical process (oxidation of ascorbic acid) occurring near the ND surface in an aqueous environment under ambient conditions.
Trvalý link: http://hdl.handle.net/11104/0311735