Decreasing Incidence of the Anencephaly in the Czech Republic: Long-Term Population-Based Study (P36)

0531734 - ÚI 2021 eng A - Abstrakt
Šípek, A. - Gregor, V. - Horáček, J. - Klaschka, Jan - Malý, Marek - Šípek jr., A.
Decreasing Incidence of the Anencephaly in the Czech Republic: Long-Term Population-Based Study (P36).
Birth Defects Research. Roč. 112, č. 11 (2020), s. 860-860. ISSN 2472-1727. E-ISSN 2472-1727.
[Annual Meeting of Society for Birth Defects Research and Prevention /60./. 25.06.2020-02.07.2020, Online]
Grant CEP: GA MZd NV17-29622A
Institucionální podpora: RVO:67985807

Anencephaly is a lethal anomaly of the central nervous system from the group of neural tube defects. The main goal of our study was to evaluate the incidence of anencephaly (and its possible trends) during long-term 53 years period. For this study, we have used data from the National Registry of Congenital Anomalies of the Czech Republic. The surveillance of Congenital anomalies has a long tradition in the Czech Republic, the official population-wide registry started in 1964. Anencephaly is one of the diagnoses that were reported from the very beginning of the surveillance program. From 1985 the Registry also includes data on prenatally diagnosed cases. We analyzed the incidence of anencephaly in births and in prenatally diagnosed cases in the 1964–2016 period. We also evaluated maternal age in these cases.
Trvalý link: http://hdl.handle.net/11104/0310354