Počet záznamů: 1
Synthesis, catalytic activity and medium fluorous recycle of fluorous analogues of PEPPSI catalysts
- 1.0525654 - ÚOCHB 2021 RIV CH eng J - Článek v odborném periodiku
Šimůnek, O. - Rybáčková, M. - Svoboda, Martin - Kvíčala, J.
Synthesis, catalytic activity and medium fluorous recycle of fluorous analogues of PEPPSI catalysts.
Journal of Fluorine Chemistry. Roč. 236, Aug (2020), č. článku 109588. ISSN 0022-1139. E-ISSN 1873-3328
Institucionální podpora: RVO:61388963
Klíčová slova: palladium complex * PEPPSI * Suzuki-Miyaura coupling * perfluorooxaalkanoate * fluorous * recycle
Obor OECD: Organic chemistry
Impakt faktor: 2.050, rok: 2020
Způsob publikování: Omezený přístup
https://www.sciencedirect.com/science/article/pii/S0022113920302864?via%3Dihub
PEPPSI complexes are air and moisture stable Pd catalysts, which can be used conveniently in many coupling reactions. With the aim to obtain Pd catalysts recyclable by fluorous separation methods, we modified the structure of commercial PEPPSI complexes by per- or polyfluoroalkylation in various positions. The modifications included the use of a linear polyfluoroalkyl group instead of one aryl group on the NHC ligand, perfluoroalkylation of pyridine ligand, and substitution of chloride ligands on Pd for perfluoroalkanoates or perfluoropolyoxaalkanoates. Comparison of catalytic activity of commercial catalysts with the modified ones in Suzuki-Miyaura cross-coupling reactions showed that the fluorous modifications mostly resulted in the increase of catalytic activity. Moreover, polyfluoroalkylation enabled efficient medium fluorous recycle of the modified catalysts using a two phase aqueous DMF/HFE 7500 ether system.
Trvalý link: http://hdl.handle.net/11104/0309767
Počet záznamů: 1