Počet záznamů: 1
Preparation of a Key Tetraene Precursor for the Synthesis of Long Acenes
- 1.0522953 - ÚOCHB 2021 RIV DE eng J - Článek v odborném periodiku
Levet, G. - Hung, N. K. - Šámal, Michal - Rybáček, Jiří - Císařová, Ivana - Jančařík, Andrej - Gourdon, A.
Preparation of a Key Tetraene Precursor for the Synthesis of Long Acenes.
European Journal of Organic Chemistry. Roč. 2020, č. 11 (2020), s. 1658-1664. ISSN 1434-193X. E-ISSN 1099-0690
Grant CEP: GA MŠMT(CZ) EF17_050/0008490
Institucionální podpora: RVO:61388963
Klíčová slova: tetraene * cycloaddition * ozonolysis * protecting groups * carboxylation
Obor OECD: Organic chemistry
Impakt faktor: 3.021, rok: 2020
Způsob publikování: Omezený přístup
https://chemistry-europe.onlinelibrary.wiley.com/doi/full/10.1002/ejoc.201901868
The tetraene 7,7-dimethoxy-2,3,5,6-tetramethylenebicyclo[2.2.1]heptane is a key compound for the preparation of a large variety of acenes protected by a carbonyl bridge. We report herein a medium scale preparation in seven steps of this valuable starting material. Diels-Alder addition between 6,6-dimethtyl fulvene and maleic anhydride, followed by carboxylation, ozonolysis of the double bond, reduction of the four ester groups, then chlorination of the alcohol groups and dehydrochlorination give the target compound in 17 % overall yield.
Trvalý link: http://hdl.handle.net/11104/0307361
Počet záznamů: 1