Serum antibodies against alpha-amylase inhibitors in celiac disease

0521158 - MBÚ 2020 CZ eng A - Abstrakt
Sánchez, Daniel - Štěpánová Honzová, S. - Hoffmanová, I. - Hábová, Věra - Szczepanková, Adéla - Tlaskalová-Hogenová, Helena - Tučková, Ludmila
Serum antibodies against alpha-amylase inhibitors in celiac disease.
Book of Proceedings. Praha: RADANAL, Ltd., 2019 - (Neuveden, N.). s. 26. ISBN ISBN 978-80-7560-245-9.
[19th International Nutrition and Diagnostics Conference - INDC. 15.10.2019-18.10.2019]
Grant CEP: GA TA ČR(CZ) TH03010019
Klíčová slova: wheat gluten * celiac disease * autoimmunity * immunce dystem
Obor OECD: Microbiology

Gliadins and related cereal proteins are note unique food stuff affects celiac disease patient´s immune system. No information is available on the adaptive immune response against the wheat AAIs. We use an immunoblot technique employing the mixture of isolated wheat AAI 0.19 and AAI 0.28 and developer a reproductible, robust ELISA test for quantification of serum OgA and IgG antibodies against wheat recombinant AAI 0.19 protein.
Trvalý link: http://hdl.handle.net/11104/0306204