HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in Arabidopsis thaliana by mediating H2A.Z depletion

0520740 - ÚEB 2020 RIV US eng J - Článek v odborném periodiku
van der Woude, A. - Perrella, C. - Snoek, L. B. - Van Hoogdalem, M. - Novák, Ondřej - Van Verk, M. C. - Van Kooten, H. N. - Zorn, L. E. - Tonckens, R. - Dongus, J. A. - Praat, M. - Stouten, E. A. - Proveniers, M. C.G. - Vellutini, E. - Patitaki, E. - Shapulatov, U. - Kohlen, W. - Balasubramanian, S. - Ljung, K. - van der Krol, A. R. - Smeekens, S. - Kaiserli, E. - van Zanten, M.
HISTONE DEACETYLASE 9 stimulates auxin-dependent thermomorphogenesis in Arabidopsis thaliana by mediating H2A.Z depletion.
Proceedings of the National Academy of Sciences of the United States of America. Roč. 116, č. 50 (2019), s. 25343-25354. ISSN 0027-8424. E-ISSN 1091-6490
Grant CEP: GA MŠMT(CZ) EF16_019/0000827
Institucionální podpora: RVO:61389030
Klíčová slova: Arabidopsis * h2a.z * hda9 * Shade avoidance * Thermomorphogenesis
Obor OECD: Biochemistry and molecular biology
Impakt faktor: 9.412, rok: 2019
Způsob publikování: Open access
http://dx.doi.org/10.1073/pnas.1911694116

Many plant species respond to unfavorable high ambient temperatures by adjusting their vegetative body plan to facilitate cooling. This process is known as thermomorphogenesis and is induced by the phytohormone auxin. Here, we demonstrate that the chromatinmodifying enzyme HISTONE DEACETYLASE 9 (HDA9) mediates thermomorphogenesis but does not interfere with hypocotyl elongation during shade avoidance. HDA9 is stabilized in response to high temperature and mediates histone deacetylation at the YUCCA8 locus, a rate-limiting enzyme in auxin biosynthesis, at warm temperatures. We show that HDA9 permits net eviction of the H2A.Z histone variant from nucleosomes associated with YUCCA8, allowing binding and transcriptional activation by PHYTOCHROME INTERACTING FACTOR 4, followed by auxin accumulation and thermomorphogenesis.
Trvalý link: http://hdl.handle.net/11104/0305410